首次发现了细菌间的相互合作与竞争导致生物被膜周期性减缓生长的新现象及其机制(Nature 2015, Science 2017);开发了定量研究细菌群体的新方法(Small Science 2022, Nature Chemical Biology 2023);揭示了细菌群体跨区域代谢交互的新模式(Nature Chemical Biology 2023);发现了细菌对抗生素以及噬菌体耐受性的新机制(Nature Chemical Biology 2024, Nature Communications 2024, Science Advances 2024)。
奖励与荣誉
2018年入选国家海外高层次人才计划青年项目
2018年入选求是科技基金会杰出青年学者
学术成果
Q. Hu, L. Huang, Y. Yang, Y. Xiang, J. Liu. Essential phage component induces resistance of bacterial community. Science Advances 10, eadp5057 (2024).
Y. Zhang, Y. Cai, X. Jin, Q. Wu, F. Bai, J. Liu. Persistent glucose consumption under antibiotic treatment protects bacterial community. Nature Chemical Biology (2024). https://doi.org/10.1038/s41589-024-01708-z
Y. Zheng, R. Chai, T. Wang, Z. Xu, Y. He, P. Shen, J. Liu. RNA polymerase stalling-derived genome instability underlies ribosomal antibiotic efficacy and resistance evolution. Nature Communications 15, 6579 (2024).
T. Wang, P. Shen, Y. He, Y. Zhang, J. Liu. Spatial transcriptome uncovers rich coordination of metabolism in E. coli K12 biofilm. Nature Chemical Biology 19, 940-950 (2023).
T. Wang, P. Shen, R. Chai, Y. He, J. Liu. Profiling of bacterial transcriptome from ultra-low input with MiniBac-seq. Environmental Microbiology 24, 5774–5787 (2022).
Y. Zhang, Y. Cai, L. Zeng, P. Liu, L. Z. Ma, J. Liu. A Microfluidic Approach for Quantitative Study of Spatial Heterogeneity in Bacterial Biofilms. Small Science 2, 2200047 (2022).
J. Liu, R. Martinez-Corral, A. Prindle, D.-Y. D. Lee, J. Larkin, M. Gabalda-Sagarra, J. Garcia-Ojalvo, G. M. Süel, Coupling between distant biofilms and emergence of nutrient time-sharing. Science 356, 638–642 (2017).
J. Liu, A. Prindle, J. Humphries, M. Gabalda-Sagarra, M. Asally, D. D. Lee, S. Ly, J. Garcia-Ojalvo, G. M. Süel, Metabolic co-dependence gives rise to collective oscillations within biofilms. Nature 523, 550–554 (2015).
Complete list of publications: https://orcid.org/0000-0002-6710-2605